Methods for Analysing and Reporting EQ-5D Data

Foreword Preface Chapter 1 An introduction to EQ-5D instruments and their applications 1.1 Measuring health using the EQ-5D1.2 What does the EQ-5D measure?1.2.1 The EQ-5D self-reported health state (EQ-5D profile)1.2.2 EQ VAS1.2.3 EQ-5D values1.2.4 What aspect of the information provided by the EQ-5D should be the primary focus on my analysis?1.3 EQ-5D data collection and data handling1.4 Before starting your analysis1.4.1Treatment of missing data - what to do, what not to do1.4.2 Planning your analysis1.5 Guide to the rest of this bookReferences Chapter 2 Analysis of EQ-5D profile data 2.1 Cross-sectional analysis: describing health at a point in time by dimension and level2.2 Longitudinal analysis: describing changes in health between two time points by dimension and level2.3 Cross sectional analysis: describing health at a point in time using profiles2.4 Longitudinal analysis: describing changes in health between two points in time using profiles2.4.1 The Paretian Classification of Health Change (PCHC)2.4.2 The probability of superiority2.4.3 Health Profile Grid (HPG)2.5 Summarising the severity of EQ-5D profiles2.5.1 The level sum score (LSS)2.5.2 The level frequency score (LFS)2.6 Analysing the informativity of EQ-5D profile data2.6.1 Shannon Indices2.6.2 Health State Density Curve (HSDC)2.6.3 Health State Density Index (HSDI) and other related indicesReferences Chapter 3 Analysis of EQ VAS data 3.1 Interpreting the EQ VAS3.2 Simple descriptive statistics and inference3.3 Modelling determinants of EQ VAS scoresReferences Chapter 4 Analysis of EQ-5D values 4.1 Value sets and their properties4.2 Positive and normative considerations in choice of value set4.3 Simple descriptive statistics and inference4.4 Examining the distribution of EQ-5D values4.5 Variance and heteroskedasticity4.6 exploring clusters in EQ-5D value distributions4.7 Regression analysis4.8 Uncertainty and sensitivity analysisReferences Chapter 5 Advanced topics 5.1 Analysing changes and differences in EQ-5D values and EQ VAS scores5.1.1 Defining the outcomes of an intervention study as a change5.1.2 Minimal Important Differences (MIDs)· Using EQ-5D MIDs· MID estimation methods5.1.3 Case-mix and risk adjustment of EQ-5D data5.2 MappingReferences Glossary of terms