Liquid Chromatography-Mass Spectrometry

A constructive evaluation of the most significant developments in liquid chromatographymass spectrometry (LCMS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines, Liquid ChromatographyMass Spectrometry, Third Edition offers a well-rounded coverage of the latest technological developments and applications. As the technology itself has matured into a reliable analytical method over the last 15 years, the most exciting developments occur in LCMS augments research into new applications. This edition places a stronger emphasis than previous editions on the impact of LCMS methods, dedicating two-thirds of the text to small-molecule and biomolecular applications such as proteomics, pharmaceutical drug discovery and development, biochemistry, clinical analysis, environmental studies, and natural products research. Supported by the most relevant literature available, each chapter examines how the strategies, technologies, and recent advancesfrom sample pretreatment to data processingin LCMS helped to shape these disciplines. Featuring new chapters and extensive revisions throughout the book, Liquid ChromatographyMass Spectrometry, Third Edition continues to provide scientists with a definitive guide and reference to the most important principles, strategies, and experimental precedents for applying LCMS to their research.